Based on prior work by Professor Nigel B Pitts and Dr Chris Longbottom of Kings College London, Reminova Ltd aims to commercialise new technologies in these fields, developing new in-office solutions for the dentistry sector and bringing applications beyond this to the consumer market.
Caries is a result of the production of acid, in the biofilm, by bacterial fermentation of free sugars on the tooth surface. If demineralization exceeds salivary and other remineralization factors, such as calcium and fluoride from toothpastes, these once hard tissues progressively break down, eventually producing cavities (holes in the teeth).
Today, dental caries remains one of the most common diseases throughout the world. Current treatment involves drilling the tooth to remove decay and filling with restorative materials such as amalgalm, resin, procelain or gold.
Reminova aims to develop new technologies that will rapidly and painlessly replace mineral lost from teeth without the need for anasthetic or analgesia. This takes forward the shift towards preventive dentistry to a new level, presenting additional opportunities for patient-friendly cosmetic applications through tooth whitening. The new technology will also seek to increase patient comfort and reduce anxiety. In short. No more drill and fill, and a safe way to improve appearance..
An Honorary Consultant in Dental Public Health to Guy’s and St Thomas’ NHS Foundation Trust. He has also been appointed by the Secretary of State to the UK Research Excellence Framework (REF 2014) Panel.
Professor Pitts graduated in Dentistry from the University of London, moved to the University of Hong Kong to help set up a new Dental School in the 1980s and returned to the UK to take up the Directorship of the Dental Health Services Research Unit at the University of Dundee, where he also served as Dean of Dentistry and Director of the Centre for Clinical Innovations.
Professor Pitts has, with his colleague Dr Chris Longbottom, been responsible for a range of commercially exploitable innovations. He also has a mature network of Oral Health Industry relationships including major multinational companies. He has 208 peer reviewed publications and 93 Chapters, Books and Equivalent Publications.
Professor Pitts has also been awarded international research prizes from: the FDI World Dental Federation, the British Dental Association Research Foundation, and the International Association for Dental Research (IADR –now holding two Distinguished Scientist Awards - for Epidemiology (1999) as well as Caries Research (2011); as well as from the European Organisation for Caries Research
Chair of the Alliance for a Cavity Free Future, Co-Chair of the International Caries Detection and Assessment System (ICDAS) Foundation. He also holds a number of degrees and Fellowships – FRSE, BDS, PhD, FDS (RCS Eng), FDS (RCS Edin), FFGDP (UK), FFPH.
He started working with Professor Nigel Pitts shortly after the latter was appointed as Director of the Dental Health Services Research Unit (DHSRU) in 1985. Chris was appointed as Lecturer in Preventive & Children’s Dentistry at Dundee Dental School in 1987, where he completed his PhD in the diagnostic aspects of Cariology in 1992. He worked with DHSRU personnel on Dental Public Health projects.
Between 1994 and 2012 Chris has been involved in grant-funded research. He was appointed Senior Lecturer in 2001 and is registered as a Specialist in Paediatric Dentistry. He was Associate director of the Centre for Clinical Innovations in Dundee and is Associate Director of the Dental Innovation and Translation Centre at KCL Dental Institute.
He is a named inventor on 19 filed patents, involving caries detection / diagnostic systems, as well as therapeutic technologies/devices. These patents range from electrical, optical and ultrasound technologies for diagnostics and therapeutics to Controlled-release technologies for therapeutic purposes.
One patent, involving a caries detection innovation which was taken forward, with a package of University, Scottish Enterprise and Angel Investor finance, to become a PLC on the London AIM market.
Dr Longbottom is currently building on previous funding and innovation work in setting up the King's College London Dental Institute’s new Innovation and Translation Centre.
No drilling, no filling, no fuss – Reminova Ltd will put tooth decay in a ‘time warp’
Dentists could soon be giving your teeth a mild ‘time warp’ to encourage them to self-repair, thanks to a new device being developed by dental researchers. Reminova Ltd, a new spin-out company from King’s College London, aims to take the pain out of tooth decay treatment by electrically reversing the process to help teeth ‘remineralise’.
The company is the first spin-out from the King’s College London Dental Innovation and Translation Centre which was launched in January 2013. This centre was formed to take research and novel technologies and turn them into products, change practice and inform policy which will improve health and healthcare internationally.
Reminova Ltd will be based in Perth, Scotland to benefit from the strong life sciences and dentistry base. It will commercialise the work of Professor Nigel Pitts and Dr Chris Longbottom, based in the Dental Institute at King’s College London. With a combined 80 years’ experience in dentistry they have previously brought dental devices to market to detect tooth decay. The company was formed in collaboration with Innova Partnerships, who commercialise healthcare and life science enterprises.
The company is currently seeking private investment to develop their remineralisation device. For a full press release and to find out more about the technology, visit